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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562758Generated: October 26, 2026

2-(Cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → 8-Bromo-2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

https://huagongshe.com/reaction/562758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252629—
Reactant8-Bromo-2-(cyclobutyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252642—
Product8-Bromo-2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252655—

Reaction Steps

Prepared similarly to Intermediate 56 from 2-(cyclopentyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067426B2
Source datasetuspto-grants-2011_11
ORD IDord-11fc62390e9b4dfaaf827f53960d09b1
Source noteuspto-grants-2011_11