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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562764Generated: October 30, 2026

2-(Cyclobutyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → 2-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

https://huagongshe.com/reaction/562764

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Cyclobutyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252601—
Reactant8-Bromo-2-(cyclohexyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252657—
Product2-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 59252649—

Reaction Steps

Prepared similarly to Intermediate 57 from 8-bromo-2-(cyclohexyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067426B2
Source datasetuspto-grants-2011_11
ORD IDord-fa8781562a1d4387b8cec3d50f46aad0
Source noteuspto-grants-2011_11