2-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine → HCID 178494008, compound

HRID 562765Notes

Reaction equation

HRID 562765 reaction equation
[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].C1(OC2NC(N)=C3C(N=2)=NC(OC)=N3)CCC1.[CH:25]1([O:31][C:32]2[N:40]=[C:39]3[C:35]([N:36]=[C:37]([O:47][CH3:48])[N:38]3C3CCCCO3)=[C:34]([NH2:49])[N:33]=2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[F:1][C:2]([F:7])([F:6])[C:3]([OH:5])=[O:4].[CH:25]1([O:31][C:32]2[NH:33][C:34]([NH2:49])=[C:35]3[C:39]([N:40]=2)=[N:38][C:37]([O:47][CH3:48])=[N:36]3)[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]1

Participants

3

Reactant 2

HCID 592526492-(Cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amineHCID 178494005HCID 178494005, compound

Product 1

HCID 178494008HCID 178494008, compound

Procedure

Prepared similarly to Intermediate 58 from 2-(cyclohexyloxy)-8-(methyloxy)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

Sources & evidence

ORD record
ord-532734ff2a8b4382b5337e3a36128d46
Source dataset
uspto-grants-2011_11
Patent number
US08067426B2

Reaction notes

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