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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562777Generated: October 31, 2026

1-Bromo-3-chloropropane → 9-(3-Chloropropyl)-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine

https://huagongshe.com/reaction/562777

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-3-chloropropaneHCID 8006—
Reactant9-(4-Chlorobutyl)-8-(methyloxy)-2-{[(1S)-1-methylpropyl]oxy}-9H-purin-6-amineHCID 59252648—
ReactantHCID 178448286HCID 178448286—
Product9-(3-Chloropropyl)-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amineHCID 59252573—

Reaction Steps

Prepared similarly to Intermediate 44 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and 1-bromo-3-chloropropane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067426B2
Source datasetuspto-grants-2011_11
ORD IDord-da9ea4a80405478496fc894350593b43
Source noteuspto-grants-2011_11