HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562813Generated: October 28, 2026
HCID 22499174, compound → HCID 22499212, compound
https://huagongshe.com/reaction/562813
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 22499174 | HCID 22499174 | — |
| Reactant | Tri(butyl)vinyltin | HCID 53438229 | — |
| Catalyst | Dichlorobis(triphenylphosphine)palladium | HCID 6102075 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22499212 | HCID 22499212 | — |
Reaction Steps
Bis-(triphenylphosphine)palladium(II)chloride (98 mg) is added to a solution of 5-bromo-8-methoxymethoxy-6-methyl-1H-quinolin-2-one (410 mg) and tributylvinyltin (603 μL) in dimethylformamide (14 mL) at room temperature. The reaction mixture is heated for 24 hours at 90° C., evaporated and purified by flash column chromatography on silica gel, eluting with 2% methanol in dichloromethane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08067437B2 |
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| Source dataset | uspto-grants-2011_11 |
|---|
| ORD ID | ord-772ba8c2956946b7b04550ffd8102bb9 |
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| Source note | uspto-grants-2011_11 |
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