1,2,3,4-Tetramethylbenzene → 3-Chloro-1-(2,3,4,5-tetramethyl-phenyl)-propan-1-one

HRID 562821Notes

Reaction equation

HRID 562821 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH3:8])=[C:4]([CH3:9])[C:3]=1[CH3:10].[Cl:11][CH2:12][CH2:13][C:14](Cl)=[O:15]>>[Cl:11][CH2:12][CH2:13][C:14]([C:7]1[CH:6]=[C:5]([CH3:8])[C:4]([CH3:9])=[C:3]([CH3:10])[C:2]=1[CH3:1])=[O:15]

Participants

3

Reactant 2

HCID 102631,2,3,4-TetramethylbenzeneHCID 693643-Chloropropionyl chloride

Product 1

HCID 138098623-Chloro-1-(2,3,4,5-tetramethyl-phenyl)-propan-1-one

Procedure

3-Chloro-1-(2,3,4,5-tetramethyl-phenyl)-propan-1-one is prepared from 1,2,3,4-tetramethyl-benzene and 3-chloro propionyl chloride by a procedure analogous to that of Preparation 1.

Workup

  1. customof Preparation 1

Sources & evidence

ORD record
ord-32225241a79746378a8d064eae207ca6
Source dataset
uspto-grants-2011_11
Patent number
US08067437B2

Reaction notes

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