HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57429031, compound → HCID 66823234, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57429031 | HCID 57429031 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66823234 | HCID 66823234 | — |
Reaction Steps
Acetic acid (R)-1-(4-benzyloxy-3-nitro-phenyl)-2-[benzyl-(2,5,6-trimethyl-indan-2-yl)-amino]-ethyl ester in a mixture of THF and toluene is stirred under hydrogen in the presence of PtO2 at room temperature for 15 hours. The mixture is filtered through celite and the filtrate is concentrated in vacuo. ES+MS m/e 549 (MH+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067437B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-b651b8ae4b144cb5b2349f0dc4e58645 |
| Source note | uspto-grants-2011_11 |