HuagongsheHuagongshe Chemistry Print Report · For research reference only
Neopentyl alcohol → HCID 66995428, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Neopentyl alcohol | HCID 6404 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Bromo-2-fluorobenzonitrile | HCID 2724900 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 66995428 | HCID 66995428 | — |
Reaction Steps
After 2,2-dimethyl-1-propanol and sodium hydride were stirred at 0° C. in DMF, 5-bromo-2-fluorobenzonitrile was added thereto, followed by reaction at room temperature to obtain 5-bromo-2-(2,2-dimethylpropoxy)benzonitrile. NMRC: 3.67 (2H, s), 6.83 (1H, d), 7.64 (1H, d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067446B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-bc562c04493f49ecbd013a37959449af |
| Source note | uspto-grants-2011_11 |