HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → 5-Bromo-2-(piperidin-1-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-Bromo-2-fluorobenzonitrile | HCID 2724900 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 5-Bromo-2-(piperidin-1-yl)benzonitrile | HCID 66995418 | — |
Reaction Steps
5-Bromo-2-fluorobenzonitrile and piperidine were heated at 80° C. in DMSO in the presence of cesium carbonate to obtain 5-bromo-2-piperidin-1-ylbenzonitrile. F: 265.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067446B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-913d37e99dcc43099b3f60b4b0977491 |
| Source note | uspto-grants-2011_11 |