Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 562890Generated: October 25, 2026

Chlorosuccinimide → Methyl 2-(3-chloro-5-cyano-4-hydroxyphenyl)isonicotinate

https://huagongshe.com/reaction/562890

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorosuccinimideHCID 31398—
ReactantMethyl 2-(3-cyano-4-hydroxyphenyl)isonicotinateHCID 136368377—
SolventAcetonitrileHCID 6342—
ProductMethyl 2-(3-chloro-5-cyano-4-hydroxyphenyl)isonicotinateHCID 136368378—

Reaction Steps

Methyl 2-(3-cyano-4-hydroxyphenyl)isonicotinate and N-chlorosuccinimide were stirred at room temperature in acetonitrile to obtain methyl 2-(3-chloro-5-cyano-4-hydroxyphenyl)isonicotinate. ES: 289.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067446B2
Source datasetuspto-grants-2011_11
ORD IDord-3bf5b5cf85fd4644a306df1eddf6503d
Source noteuspto-grants-2011_11