Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl propiolate | HCID 12182 | — |
| Reactant | HCID 130172856 | HCID 130172856 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 66995258 | HCID 66995258 | — |
Reaction Steps
3-Cyano-N-hydroxy-4-methoxybenzenecaboximidoyl chloride, ethyl propiolate and triethylamine were dissolved in a THF solution, followed by stirring at 40° C. to obtain ethyl 3-(3-cyano-4-methoxyphenyl)-5-isoxazolecarboxylate. AP: 295.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08067446B2 |
|---|
| Source dataset | uspto-grants-2011_11 |
|---|
| ORD ID | ord-00443436f7c04556a48be571064c129d |
|---|
| Source note | uspto-grants-2011_11 |
|---|
