HRID563430

反应详情

EQUATION

反应方程式

HRID 563430 的结构方程式

PROCEDURE

实验过程

Example 152 was prepared from 3-(1H-indazol-5-yl)-2-methyl-3-phenylpropanoic acid (10 and 30 mg, 0.03 and 0.88 mmol) and 1,3,4-thiadiazol-2-amine using General Coupling Method A to give 4 mg (% yield) and 6 mg of the respective diastereomers. MS found: (M+H)+=426. NMR(CDCl3) δ 8.8 (s, 1H); 7.97-8.01 (d, 1H); 7.60 (s, 1H) 7.0-7.59 (m, 12H); 4.85 (d, 1H); 4.56 (d, 1H).

WORKUP

后处理

  1. customto give 4 mg (% yield) and 6 mg of the respective diastereomers