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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563478Generated: October 31, 2026

Glycinamide hydrochloride → {2'-[(Carbamoylmethyl-amino)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/563478

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycinamide hydrochlorideHCID 2723639—
Reactant(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633167—
Product{2'-[(Carbamoylmethyl-amino)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66634341—

Reaction Steps

Prepared according to the procedure described in Example 4, Step 1, using the following starting materials: (2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and glycinamide hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-d4c13e81042b4f8d9b6452cd914642d2
Source noteuspto-grants-2011_11