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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563481Generated: October 25, 2026

Ethylamine → (2'-Ethylaminomethyl-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/563481

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant(6-Fluoro-2'-formyl-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 86633169—
Product(2'-Ethylaminomethyl-6-fluoro-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 66603778—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 5, using the following starting materials: (6-fluoro-2′-formyl-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and ethylamine (2M in THF).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-11badbb6f23e480ea857e5101718f91e
Source noteuspto-grants-2011_11