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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563486Generated: October 27, 2026

Acetyl chloride → {2'-[(Acetyl-cyclopropyl-amino)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/563486

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant(2'-Cyclopropylaminomethyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl esterHCID 66607165—
Product{2'-[(Acetyl-cyclopropyl-amino)-methyl]-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66607123—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-cyclopropylaminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid methyl ester and acetyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-5abff1b8a6f54bfa98783ecb8a09ea17
Source noteuspto-grants-2011_11