Acetyl chloride → HCID 66611879, compound

HRID 563508Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:28])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH:23]([NH:25][CH2:26][CH3:27])[CH3:24])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[C:29](Cl)(=[O:31])[CH3:30]>>[CH3:1][O:2][C:3](=[O:28])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:21])([F:20])[F:22])=[CH:15][C:14]=2[CH:23]([N:25]([C:29](=[O:31])[CH3:30])[CH2:26][CH3:27])[CH3:24])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 66606804HCID 66606804, compound

Product 1

HCID 66611879HCID 66611879, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: [2′-(1-ethylamino-ethyl)-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester and acetyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-e7c3c0f3cf9b47aabccc5b118ca3a4e5
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08067445B2

Reaction notes

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