Ethylamine → (2-Bromo-5-trifluoromethyl-benzyl)-ethyl-amine
Reaction equation
[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH:4]=O.[CH2:14]([NH2:16])[CH3:15]>>[Br:1][C:2]1[CH:9]=[CH:8][C:7]([C:10]([F:13])([F:12])[F:11])=[CH:6][C:3]=1[CH2:4][NH:16][CH2:14][CH3:15]Participants
3
Procedure
Prepared according to the procedure described in Example 33, Step 4, using the following starting materials: 2-bromo-5-(trifluoromethyl)benzaldehyde and ethylamine (2M in THF).
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-960e108442a243188a3810389b0d4115
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08067445B2
Reaction notes
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