2-Bromo-5-nitrobenzaldehyde → (2'-Formyl-6-methoxy-4'-nitro-biphenyl-3-yl)-acetic acid ethyl ester

HRID 563538Notes

Reaction equation

HRID 563538 reaction equation
Br[C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[CH:4]=[O:5].[CH2:13]([O:15][C:16](=[O:35])[CH2:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20](B2OC(C)(C)C(C)(C)O2)[CH:19]=1)[CH3:14]>>[CH2:13]([O:15][C:16](=[O:35])[CH2:17][C:18]1[CH:19]=[C:20]([C:2]2[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=2[CH:4]=[O:5])[C:21]([O:24][CH3:25])=[CH:22][CH:23]=1)[CH3:14]

Participants

3

Reactant 2

HCID 111389422-Bromo-5-nitrobenzaldehydeHCID 58120060[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester

Product 1

HCID 58149145(2'-Formyl-6-methoxy-4'-nitro-biphenyl-3-yl)-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 2-bromo-5-nitro-benzaldehyde and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2e5f537f62e846ab94c52ead30f28b7b
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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