Ethylamine → (2'-Ethylaminomethyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

HRID 563547Notes

Reaction equation

HRID 563547 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:14]=2[CH:21]=O)[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[CH2:24]([NH2:26])[CH3:25]>>[CH3:1][O:2][C:3](=[O:23])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:14]=2[CH2:21][NH:26][CH2:24][CH3:25])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 6341EthylamineHCID 58148902(2'-Formyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

Product 1

HCID 58148841(2'-Ethylaminomethyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

Procedure

Prepared according to the procedure described in Example 33, Step 4, using the following starting materials: (2′-formyl-6,5′-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester and ethylamine (2M in THF).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-dec0dc28f614449780492071af4880d9
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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