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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563561Generated: October 31, 2026

Methanol → HCID 86651109, compound

https://huagongshe.com/reaction/563561

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHCID 86651107HCID 86651107—
CatalystSulfuric AcidHCID 1118—
ProductHCID 86651109HCID 86651109—

Reaction Steps

(R)-2-(2′-Ethylaminomethyl-5,4′-bis-trifluoromethyl-biphenyl-3-yl)-propionic acid (0.04 g, 0.10 mmol) in MeOH (2 mL) was treated with 2 drops of sulfuric acid at room temperature overnight. The mixture was concentrated, and the crude material was used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-1424c864a1b540b5aa9c6eda7dc7a1af
Source noteuspto-grants-2011_11