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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563568Generated: October 30, 2026

5-Bromo-2-ethoxypyridine → [2'-[(tert-Butoxycarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl ester

https://huagongshe.com/reaction/563568

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-ethoxypyridineHCID 817237—
Reactant[2'-[(Tert-butoxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4'-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-3-yl]-acetic acid ethyl esterHCID 58149092—
Product[2'-[(tert-Butoxycarbonyl-ethyl-amino)-methyl]-4'-(6-ethoxy-pyridin-3-yl)-6-methoxy-biphenyl-3-yl]-acetic acid ethyl esterHCID 58149276—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: [2′-[(tert-butoxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-biphenyl-3-yl]-acetic acid ethyl ester and 5-bromo-2-ethoxypyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-8f535ce68def4735bdc6d06f63c34bfa
Source noteuspto-grants-2011_11