2,2,2-Trifluoroethylamine hydrochloride → HCID 86651116, compound

HRID 563609Notes

Reaction equation

HRID 563609 reaction equation
[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH:24]=O)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].Cl.[F:28][C:29]([F:33])([F:32])[CH2:30][NH2:31]>>[CH2:1]([O:3][C:4](=[O:26])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:21])([F:23])[F:22])=[CH:16][C:15]=2[CH2:24][NH:31][CH2:30][C:29]([F:33])([F:32])[F:28])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 97722,2,2-Trifluoroethylamine hydrochlorideHCID 86633171(2'-Formyl-6-methoxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester

Product 1

HCID 86651116HCID 86651116, compound

Procedure

Prepared according to the procedure described in Example 4, Step 1, using the following starting materials: (2′-formyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and 2,2,2-trifluoroethylamine hydrochloride.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-399882b2e20b42ba8ff1dd65c242bd44
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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