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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563649Generated: November 2, 2026

HCID 66606831, compound → HCID 66607287, compound

https://huagongshe.com/reaction/563649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66606831HCID 66606831—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 66607287HCID 66607287—

Reaction Steps

To a solution of 2-{2′-[(benzyloxycarbonyl-ethyl-amino)-methyl]-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl}-propionic acid ethyl ester (0.11 mmol) in EtOH (12 mL) was added 10% palladium on carbon (0.050 g), and the reaction was stirred under a balloon of H2 at room temperature for 1 hour. The mixture was filtered through a pad of Celite and rinsed with EtOH. The filtrate was concentrated to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-ff9ca4b16b3347f18562255d616d31f9
Source noteuspto-grants-2011_11