Ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate → {6-Benzyloxy-2'-[(benzyloxycarbonyl-ethyl-amino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester

Participants

Role	Name	HCID	Charge
Reactant	Ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate	HCID 18620085	—
Reactant	(Ethyl)[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethylbenzyl]carbamic acid benzyl ester	HCID 66603618	—
Product	{6-Benzyloxy-2'-[(benzyloxycarbonyl-ethyl-amino)-methyl]-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester	HCID 66607697	—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid benzyl ester and (4-benzyloxy-3-bromo-phenyl)-acetic acid ethyl ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08067445B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-b502e8274b084a96b22b712cb1fcc6cd
Source note	uspto-grants-2011_11