HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Bromo-4-ethoxy-phenyl)-acetic acid ethyl ester → {2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-6-ethoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Bromo-4-ethoxy-phenyl)-acetic acid ethyl ester | HCID 58148901 | — |
| Reactant | (Ethyl)[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethylbenzyl]carbamic acid benzyl ester | HCID 66603618 | — |
| Product | {2'-[(Benzyloxycarbonyl-ethyl-amino)-methyl]-6-ethoxy-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester | HCID 66606859 | — |
Reaction Steps
Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid benzyl ester and (3-bromo-4-ethoxy-phenyl)-acetic acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067445B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-ddcd2833f4de451b9411028fec7b169f |
| Source note | uspto-grants-2011_11 |