Acetyl chloride → HCID 66968596, compound

HRID 563706Notes

Reaction equation

[CH2:1]([NH:3][CH2:4][C:5]1[CH:10]=[C:9]([C:11]([F:14])([F:13])[F:12])[CH:8]=[CH:7][C:6]=1[C:15]1[C:20]([O:21][CH3:22])=[CH:19][CH:18]=[C:17]([C:23]([F:28])([F:27])[C:24]([OH:26])=[O:25])[CH:16]=1)[CH3:2].[C:29](Cl)(=[O:31])[CH3:30]>>[C:29]([CH2:2][CH2:1][NH:3][CH2:4][C:5]1[CH:10]=[C:9]([C:11]([F:13])([F:14])[F:12])[CH:8]=[CH:7][C:6]=1[C:15]1[C:20]([O:21][CH3:22])=[CH:19][CH:18]=[C:17]([C:23]([F:27])([F:28])[C:24]([OH:26])=[O:25])[CH:16]=1)(=[O:31])[CH3:30]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 66607357HCID 66607357, compound

Product 1

HCID 66968596HCID 66968596, compound

Procedure

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl)-difluoro-acetic acid and acetyl chloride.

Workup

customPrepared

Sources & evidence

ORD record: ord-d605889a88c54513bd2c7a9ad95c0cf0
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08067445B2

Reaction notes

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