HRID563712

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79882

2,2-Dimethyl-1-propylamine

C5H13N

反应SMILES：CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=NC#N)Oc2ccccc2)c1

HCID87085982

未命名化合物

PRODUCTS

产物

反应SMILES：CCOC(=O)Cc1ccc(OC)c(-c2ccc(C(F)(F)F)cc2CN(CC)C(=NCC(C)(C)C)NC#N)c1

HCID87072103

未命名化合物

PROCEDURE

实验过程

Prepared according to the procedure described in Example 33, Step 6, using the following starting materials: [2′-(3-cyano-1-ethyl-2-phenyl-isoureidomethyl)-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid ethyl ester and neopentylamine.

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-3fc0ead7fe1c473e8989767b46a9876b
来源数据集: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08067445B2
来源说明: uspto-grants-2011_11

反应SMILES

[CH2:1]([O:3][C:4](=[O:39])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]([CH2:37][CH3:38])[C:26](=[N:34][C:35]#[N:36])OC2C=CC=CC=2)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[CH2:40]([NH2:45])[C:41]([CH3:44])([CH3:43])[CH3:42]>>[CH2:1]([O:3][C:4](=[O:39])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:21])[F:23])=[CH:16][C:15]=2[CH2:24][N:25]([CH2:37][CH3:38])[C:26]([NH:34][C:35]#[N:36])=[N:45][CH2:40][C:41]([CH3:44])([CH3:43])[CH3:42])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]