Neopentylamine → HCID 87072103, compound

HRID 563712Notes

Reaction equation

HRID 563712 reaction equation
[CH2:1]([O:3][C:4](=[O:39])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]([CH2:37][CH3:38])[C:26](=[N:34][C:35]#[N:36])OC2C=CC=CC=2)[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[CH2:40]([NH2:45])[C:41]([CH3:44])([CH3:43])[CH3:42]>>[CH2:1]([O:3][C:4](=[O:39])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:21])[F:23])=[CH:16][C:15]=2[CH2:24][N:25]([CH2:37][CH3:38])[C:26]([NH:34][C:35]#[N:36])=[N:45][CH2:40][C:41]([CH3:44])([CH3:43])[CH3:42])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 79882NeopentylamineHCID 87085982HCID 87085982, compound

Product 1

HCID 87072103HCID 87072103, compound

Procedure

Prepared according to the procedure described in Example 33, Step 6, using the following starting materials: [2′-(3-cyano-1-ethyl-2-phenyl-isoureidomethyl)-6-methoxy-4′-trifluoromethyl-biphenyl-3-yl]-acetic acid ethyl ester and neopentylamine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3fc0ead7fe1c473e8989767b46a9876b
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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