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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563737Generated: October 31, 2026

4-Fluorobenzyl carbonochloridate → (2'-{[Ethyl-(4-fluoro-benzyloxycarbonyl)-amino]-methyl}-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/563737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl carbonochloridateHCID 13292926—
Reactant(2'-Ethylaminomethyl-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl esterHCID 66607502—
Product(2'-{[Ethyl-(4-fluoro-benzyloxycarbonyl)-amino]-methyl}-6-methoxy-5'-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl esterHCID 66607818—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′-ethylaminomethyl-6-methoxy-5′-trifluoromethyl-biphenyl-3-yl)-acetic acid ethyl ester and 4-fluorobenzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-9fc1a3ba06124813b762e3f617da46ef
Source noteuspto-grants-2011_11