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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563746Generated: October 27, 2026

4-Fluorobenzyl carbonochloridate → (2'-{[Ethyl-(4-fluoro-benzyloxycarbonyl)-amino]-methyl}-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester

https://huagongshe.com/reaction/563746

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzyl carbonochloridateHCID 13292926—
Reactant(2'-Ethylaminomethyl-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl esterHCID 58148841—
Product(2'-{[Ethyl-(4-fluoro-benzyloxycarbonyl)-amino]-methyl}-6,5'-dimethoxy-biphenyl-3-yl)-acetic acid methyl esterHCID 58149192—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 6, using the following starting materials: (2′ ethylaminomethyl-6,5′-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester and 4-fluorobenzyl chloroformate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-c9b7ab41118b49a3a792b79ea7e1e830
Source noteuspto-grants-2011_11