Benzyl isocyanate → [2'-(3-Benzyl-1-ethyl-ureidomethyl)-6,5'-dimethoxy-biphenyl-3-yl]-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:14]=2[CH2:21][NH:22][CH2:23][CH3:24])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1.[CH2:26]([N:33]=[C:34]=[O:35])[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:1][O:2][C:3](=[O:25])[CH2:4][C:5]1[CH:6]=[C:7]([C:13]2[CH:18]=[C:17]([O:19][CH3:20])[CH:16]=[CH:15][C:14]=2[CH2:21][N:22]([CH2:23][CH3:24])[C:34]([NH:33][CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:35])[C:8]([O:11][CH3:12])=[CH:9][CH:10]=1Participants
3
Procedure
Prepared according to the procedure described in Example 95, Step 1, using the following starting materials: (2′-ethylaminomethyl-6,5′-dimethoxy-biphenyl-3-yl)-acetic acid methyl ester and benzyl isocyanate.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-c9967e7999744133bc30f6ba40a9c5fd
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08067445B2
Reaction notes
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