6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline → HCID 58149245, compound

HRID 563760Notes

Reaction equation

HRID 563760 reaction equation
[CH2:1]([O:3][C:4](=[O:23])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17](Br)=[CH:16][C:15]=2[CH:21]=[O:22])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2].[N:24]1[C:33]2[C:28](=[CH:29][C:30](B3OC(C)(C)C(C)(C)O3)=[CH:31][CH:32]=2)[CH:27]=[CH:26][CH:25]=1>>[CH2:1]([O:3][C:4](=[O:23])[CH2:5][C:6]1[CH:7]=[C:8]([C:14]2[CH:19]=[CH:18][C:17]([C:30]3[CH:29]=[C:28]4[C:33](=[CH:32][CH:31]=3)[N:24]=[CH:25][CH:26]=[CH:27]4)=[CH:16][C:15]=2[CH:21]=[O:22])[C:9]([O:12][CH3:13])=[CH:10][CH:11]=1)[CH3:2]

Participants

3

Reactant 2

HCID 162177846-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolineHCID 58148806HCID 58148806, compound

Product 1

HCID 58149245HCID 58149245, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: (4′-bromo-2′-formyl-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester and 6-quinolineboronic acid pinacol ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-08d5016f817d49d28cfd0b5dcf182590
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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