HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563769Generated: October 25, 2026
Hydrochloric Acid → Methyl 2-(5-bromo-2-methoxyphenyl)acetate
https://huagongshe.com/reaction/563769
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 5-Bromo-2-methoxyphenylacetic acid | HCID 555306 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Methyl 2-(5-bromo-2-methoxyphenyl)acetate | HCID 21999895 | — |
Reaction Steps
5-Bromo-2-methoxyphenylacetic acid (0.900 g, 3.67 mmol) in MeOH (20 mL) was treated with 4N HCl in 1,4-dioxane (4 mL) and stirred at 80° C. for 6 hours. The mixture was concentrated to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08067445B2 |
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| Source dataset | uspto-grants-2011_11 |
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| ORD ID | ord-e62d1787046a4c42a46460995294e673 |
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| Source note | uspto-grants-2011_11 |
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