Benzyl Alcohol → (3-Benzyloxy-5-trifluoromethyl-phenyl)-acetic acid

HRID 563777Notes

Reaction equation

HRID 563777 reaction equation
F[C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH2:16]([OH:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([O:23][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 27591723-Fluoro-5-(trifluoromethyl)phenylacetic acid

Product 1

HCID 59644613(3-Benzyloxy-5-trifluoromethyl-phenyl)-acetic acid

Procedure

Prepared according to the procedure described in Example 185, Step 1, using the following starting materials: 3-fluoro-5-(trifluoromethyl)phenylacetic acid and benzyl alcohol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-828b3b77570e4802bd0ffd4440dcea44
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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