Benzyl Alcohol → (3-Benzyloxy-4-chloro-phenyl)-acetic acid

HRID 563779Notes

Reaction equation

HRID 563779 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=[O:10])=[CH:4][C:3]=1F.[CH2:13]([OH:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:13]([O:20][C:3]1[CH:4]=[C:5]([CH2:8][C:9]([OH:11])=[O:10])[CH:6]=[CH:7][C:2]=1[Cl:1])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 38149542-(4-Chloro-3-fluorophenyl)acetic acid

Product 1

HCID 58149177(3-Benzyloxy-4-chloro-phenyl)-acetic acid

Procedure

Prepared according to the procedure described in Example 185, Step 1, using the following starting materials: 4-chloro-3-fluorophenylacetic acid and benzyl alcohol.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fd6d12ad967c46758bcccd2379d4cd76
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

Loading…