Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → 2-(5-Bromo-2-fluorophenyl)acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 2-(5-Bromo-2-fluorophenyl)acetonitrile | HCID 23509631 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(5-Bromo-2-fluorophenyl)acetic acid | HCID 3584690 | — |
반응 단계
(5-Bromo-2-fluoro-phenyl)-acetonitrile (0.5 g, 2.3 mmol) was treated with acetic acid (2 mL) and sulfuric acid (2 mL) in H2O (2 mL) at 95° C. for 5 hours. Aqueous worked-up afforded the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08067445B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-77d85f3bebe94d1f845b7646e2bfdd2d |
| 출처 메모 | uspto-grants-2011_11 |