Methyl 2-(3-bromo-5-chlorophenyl)acetate → HCID 66607932, compound

HRID 563792Notes

Reaction equation

HRID 563792 reaction equation
[CH2:1]([N:3]([CH2:9][C:10]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[CH:12][C:11]=1B1OC(C)(C)C(C)(C)O1)[C:4]([CH:6]1[CH2:8][CH2:7]1)=[O:5])[CH3:2].[CH3:29][O:30][C:31](=[O:41])[CH2:32][C:33]1[CH:38]=[C:37]([Cl:39])[CH:36]=[C:35](Br)[CH:34]=1>>[CH3:29][O:30][C:31](=[O:41])[CH2:32][C:33]1[CH:34]=[C:35]([C:11]2[CH:12]=[CH:13][C:14]([C:16]([F:17])([F:18])[F:19])=[CH:15][C:10]=2[CH2:9][N:3]([C:4]([CH:6]2[CH2:7][CH2:8]2)=[O:5])[CH2:1][CH3:2])[CH:36]=[C:37]([Cl:39])[CH:38]=1

Participants

3

Reactant 2

HCID 58149292Methyl 2-(3-bromo-5-chlorophenyl)acetateHCID 66607375Cyclopropanecarboxylic acid ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-amide

Product 1

HCID 66607932HCID 66607932, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: cyclopropanecarboxylic acid ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]amide and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-afaa9639502a4e2591a70a6ba65274f0
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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