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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563795Generated: October 31, 2026

Methyl 2-(3-bromo-5-chlorophenyl)acetate → {2'-[(Acetyl-ethyl-amino)-methyl]-5-chloro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl ester

https://huagongshe.com/reaction/563795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-bromo-5-chlorophenyl)acetateHCID 58149292—
ReactantN-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamideHCID 66608096—
Product{2'-[(Acetyl-ethyl-amino)-methyl]-5-chloro-4'-trifluoromethyl-biphenyl-3-yl}-acetic acid methyl esterHCID 66607284—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: N-ethyl-N-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-acetamide and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-0ce338621e394f2b9b72a4243ee601e4
Source noteuspto-grants-2011_11