Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 563798Generated: October 30, 2026

3-Benzyl-1-ethyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-urea → [2'-(3-Benzyl-1-ethyl-ureidomethyl)-5,4'-bis-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl ester

https://huagongshe.com/reaction/563798

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Benzyl-1-ethyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-ureaHCID 66607126—
ReactantHCID 86651106HCID 86651106—
Product[2'-(3-Benzyl-1-ethyl-ureidomethyl)-5,4'-bis-trifluoromethyl-biphenyl-3-yl]-acetic acid methyl esterHCID 86651131—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 3-benzyl-1-ethyl-1-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-urea and (3-trifluoromethanesulfonyloxy-5-trifluoromethyl-phenyl)-acetic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08067445B2
Source datasetuspto-grants-2011_11
ORD IDord-01f9270167294317a58eb9eeeae4bb77
Source noteuspto-grants-2011_11