HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66607775, compound → HCID 66607438, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66607775 | HCID 66607775 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66607438 | HCID 66607438 | — |
Reaction Steps
A solution of {2′-[(benzyloxycarbonyl-ethyl-amino)-methyl]-5-fluoro-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid (0.025 g, 0.05 mmol) and 10% palladium on carbon (catalytic) in MeOH was hydrogenated under a balloon of H2 at room temperature for 2 hours. The mixture was filtered through a pad of Celite, and the filtrate was concentrated to give the title compound. M+H is 382.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067445B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-c5e8e8d49bd54409b854598122fd7e5e |
| Source note | uspto-grants-2011_11 |