Methyl 2-(3-bromo-5-chlorophenyl)acetate → HCID 66607005, compound

HRID 563801Notes

Reaction equation

HRID 563801 reaction equation
[CH2:1]([O:8][C:9](=[O:33])[N:10]([CH2:31][CH3:32])[CH2:11][C:12]1[CH:17]=[C:16]([C:18]([F:21])([F:20])[F:19])[CH:15]=[CH:14][C:13]=1B1OC(C)(C)C(C)(C)O1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:34][O:35][C:36](=[O:46])[CH2:37][C:38]1[CH:43]=[C:42]([Cl:44])[CH:41]=[C:40](Br)[CH:39]=1>>[CH3:34][O:35][C:36](=[O:46])[CH2:37][C:38]1[CH:39]=[C:40]([C:13]2[CH:14]=[CH:15][C:16]([C:18]([F:20])([F:21])[F:19])=[CH:17][C:12]=2[CH2:11][N:10]([C:9]([O:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[O:33])[CH2:31][CH3:32])[CH:41]=[C:42]([Cl:44])[CH:43]=1

Participants

3

Reactant 2

HCID 58149292Methyl 2-(3-bromo-5-chlorophenyl)acetateHCID 66603618(Ethyl)[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethylbenzyl]carbamic acid benzyl ester

Product 1

HCID 66607005HCID 66607005, compound

Procedure

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzyl]-carbamic acid benzyl ester and (3-bromo-5-chloro-phenyl)-acetic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7e636a6288534b0094420b01d55e29ee
Source dataset
uspto-grants-2011_11
Patent number
US08067445B2

Reaction notes

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