Methyl iodide → HCID 66607370, compound

HRID 563823Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:32])[CH2:5][C:6]1[CH:7]=[C:8]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:22])([F:21])[F:20])=[CH:15][C:14]=2[CH2:23][N:24]([C:27]([CH:29]2[CH2:31][CH2:30]2)=[O:28])[CH2:25][CH3:26])[CH:9]=[C:10]([Cl:12])[CH:11]=1)[CH3:2].I[CH3:34]>>[CH2:1]([O:3][C:4](=[O:32])[CH:5]([C:6]1[CH:7]=[C:8]([C:13]2[CH:18]=[CH:17][C:16]([C:19]([F:21])([F:20])[F:22])=[CH:15][C:14]=2[CH2:23][N:24]([C:27]([CH:29]2[CH2:30][CH2:31]2)=[O:28])[CH2:25][CH3:26])[CH:9]=[C:10]([Cl:12])[CH:11]=1)[CH3:34])[CH3:2]

Participants

Reactant 2

HCID 6328Methyl iodide

HCID 66607259HCID 66607259, compound

Product 1

HCID 66607370HCID 66607370, compound

Procedure

Prepared according to the procedure described in Example 213, Step 5, using the following starting materials: {5-chloro-2′-[(cyclopropanecarbonyl-ethyl-amino)-methyl]-4′-trifluoromethyl-biphenyl-3-yl}-acetic acid ethyl ester and iodomethane.

Workup

customPrepared

Sources & evidence

ORD record: ord-7a6ead44cd88494ab69bab9829126067
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08067445B2

Reaction notes

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