Salicylaldehyde oxime → Methyl[5-(4-chlorophenyl)-3-methyl-1-(1,3-thiazol-5-yl)-1h-pyrazol-4-yl]acetate

Participants

Reaction Steps

Methyl[5-(4-chlorophenyl)-3-methyl-1H-pyrazol-4-yl]acetate (1.0 g, 3.77 mmol), 5-bromothiazole (0.526 g, 3.21 mmol), salicylaldoxime (0.103 g, 0.75 mmol), Cu2O (0.027 g, 0.18 mmol), Cs2CO3 (1.477 g, 4.53 mmol) and acetonitrile (4.8 ml) were introduced successively into a vessel which had been dried by heating and cooled under a stream of argon.

Provenance & Evidence