HRID564055

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6354

Ethylene oxide

C2H4O

HCID67006753

tert-Butyl 6-iodo-3,4-dihydroisoquinoline-2(1H)-carboxylate

C14H18INO2

PRODUCTS

生成物

HCID67006783

1,1-Dimethylethyl 3,4-dihydro-6-(2-hydroxyethyl)-2(1H)-isoquinolinecarboxylate

C16H23NO3

PROCEDURE

实验过程

6-(2-Hydroxy-ethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester is prepared as example 7c from 8.30 g (23.1 mmol) 6-iodo-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester (preparation 10a) and 4.07 g (92.4 mmol) oxirane.