HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Benzyloxy-2(1H)-pyridone → 4-Benzyloxy-1-[2-(3-fluoro-4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Benzyloxy-2(1H)-pyridone | HCID 3607724 | — |
| Edukt | 4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006842 | — |
| Edukt | 2-Bromo-1-(3-fluoro-4-hydroxymethyl-phenyl)-ethanone | HCID 86623686 | — |
| Produkt | 4-Benzyloxy-1-[2-(3-fluoro-4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006840 | — |
Reaktionsschritte
4-Benzyloxy-1-[2-(3-fluoro-4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one is prepared following preparation 15b from 193 mg (0.93 mmol) 4-benzyloxy-1H-pyridin-2-one and 230 mg (0.93 mmol) 2-bromo-1-(3-fluoro-4-hydroxymethyl-phenyl)-ethanone (preparation 16f).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08067590B2 |
| Quelldatensatz | uspto-grants-2011_11 |
| ORD ID | ord-60056c118d7144388711ff48830013a2 |
| Quellennotiz | uspto-grants-2011_11 |