HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(benzyloxy)pyridazin-3(2H)-one → 5-Benzyloxy-2-{2-[4-(1-hydroxy-ethyl)-phenyl]-2-oxo-ethyl}-2H-pyridazin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(benzyloxy)pyridazin-3(2H)-one | HCID 59822107 | — |
| Reactant | 4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006842 | — |
| Reactant | 2-Bromo-1-[4-(1-hydroxy-ethyl)-phenyl]ethanone | HCID 86623690 | — |
| Product | 5-Benzyloxy-2-{2-[4-(1-hydroxy-ethyl)-phenyl]-2-oxo-ethyl}-2H-pyridazin-3-one | HCID 67006598 | — |
Reaction Steps
5-Benzyloxy-2-{2-[4-(1-hydroxy-ethyl)-phenyl]-2-oxo-ethyl}-2H-pyridazin-3-one is prepared following preparation 15b (DMSO as solvent) from 624 mg (3.09 mmol) 5-benzyloxy-2H-pyridazin-3-one (preparation 5c) and 750 mg (3.09 mmol) 2-bromo-1-[4-(1-hydroxy-ethyl)phenyl]-ethanone (preparation 30a).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067590B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-b727ebec21244ce78318ce0cc357d701 |
| Source note | uspto-grants-2011_11 |