4-Acetamidopiperidine → N-[1-(4-{2-[4-(Furan-3-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	4-Acetamidopiperidine	HCID 1445156	—
Reactant	1-[2-(4-bromomethylphenyl)-ethyl]-4-(furan-3-ylmethoxy)-1H-pyridin-2-one	HCID 67006963	—
Product	N-[1-(4-{2-[4-(Furan-3-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide	HCID 58042717	—

Reaction Steps

N-[1-(4-{2-[4-(Furan-3-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide is prepared as example 5.1c from 150 mg (85% purity, 0.33 mmol) 1-[2-(4-bromomethylphenyl)-ethyl]-4-(furan-3-ylmethoxy)-1H-pyridin-2-one (example 5.1b) and 187 mg (1.31 mmol) N-piperidin-4-yl-acetamide.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08067590B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-c9ba4b5c656d4f79b59d109f9d4ff0bd
Source note	uspto-grants-2011_11