HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 58042773, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Acetamidopiperidine | HCID 1445156 | — |
| Reactant | HCID 67006550 | HCID 67006550 | — |
| Product | HCID 58042773 | HCID 58042773 | — |
Reaction Steps
N-[1-(4-{2-[4-(4-Fluoro-benzyloxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide is prepared as example 7.1c from 80 mg (0.19 mmol) 1-[2-(4-bromomethyl-phenyl)ethyl]-4-(4-fluoro-benzyloxy)-1H-pyridin-2-one (example 7.1b), 41 mg (0.29 mmol) N-piperidin-4-yl-acetamide and 70 μL (0.40 mmol) N-ethyl-diisopropylamine as base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067590B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-5281d59f9cd345219660480bed49bd98 |
| Source note | uspto-grants-2011_11 |