HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Acetamidopiperidine → N-[1-(4-{2-[4-(3-Methyl-pyridin-2-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Acetamidopiperidine | HCID 1445156 | — |
| Reactant | 1-[2-(4-Bromomethyl-phenyl)-ethyl]-4-(3-methyl-pyridin-2-ylmethoxy)-1H-pyridin-2-one | HCID 67006912 | — |
| Product | N-[1-(4-{2-[4-(3-Methyl-pyridin-2-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide | HCID 58042783 | — |
Reaction Steps
N-[1-(4-{2-[4-(3-Methyl-pyridin-2-ylmethoxy)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide is prepared as example 14.1c from 100 mg (0.24 mmol) 1-[2-(4-bromomethyl-phenyl)-ethyl]-4-(3-methyl-pyridin-2-ylmethoxy)-1H-pyridin-2-one (example 14.1b) and 138 mg (0.97 mmol) N-piperidin-4-yl-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067590B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-0f106c282ce0417b93448420dee15aad |
| Source note | uspto-grants-2011_11 |