4-Acetamidopiperidine → N-[1-(4-{2-[4-(Benzyl-methyl-amino)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide

Participants

Role	Name	HCID	Charge
Reactant	4-Acetamidopiperidine	HCID 1445156	—
Reactant	4-(Benzyl-methyl-amino)-1-[2-(4-bromomethyl-phenyl)-ethyl]-1H-pyridin-2-one	HCID 58042725	—
Product	N-[1-(4-{2-[4-(Benzyl-methyl-amino)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide	HCID 58042866	—

Reaction Steps

N-[1-(4-{2-[4-(Benzyl-methyl-amino)-2-oxo-2H-pyridin-1-yl]-ethyl}-benzyl)-piperidin-4-yl]-acetamide is prepared as example 30.1 from 150 mg (0.37 mmol) 4-(benzyl-methyl-amino)-1-[2-(4-bromomethyl-phenyl)-ethyl]-1H-pyridin-2-one (preparation 14d) and 259 mg (1.82 mmol) N-piperidin-4-yl-acetamide.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08067590B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-3fb7f4fae76244699fde499bee309fb3
Source note	uspto-grants-2011_11