HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(benzyloxy)pyridazin-3(2H)-one → HCID 67007394, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(benzyloxy)pyridazin-3(2H)-one | HCID 59822107 | — |
| Reactant | 4-Benzyloxy-1-[2-(4-hydroxymethyl-phenyl)-2-oxo-ethyl]-1H-pyridin-2-one | HCID 67006842 | — |
| Reactant | HCID 86623687 | HCID 86623687 | — |
| Product | HCID 67007394 | HCID 67007394 | — |
Reaction Steps
5-Benzyloxy-2-{2-[5-(2-chloro-benzyl)-4,5,6,7-tetrahydro-thieno[3,2-c]pyridin-2-yl]-2-oxo-ethyl}-2H-pyridazin-3-one is prepared following preparation 15b (in DMSO as solvent; purification via reversed HPLC chromatography) from 500 mg (2.47 mmol) 5-benzyloxy-2H-pyridazin-3-one (preparation 5c) and 1.03 g (2.72 mmol) 2-chloro-1-[5-(2-chloro-benzyl)-3a,4,5,6,7,7a-hexahydro-thieno[3,2-c]pyridin-2-yl]-ethanone (preparation 24).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08067590B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-387dfb58cbc94e5ea5c7503131c99308 |
| Source note | uspto-grants-2011_11 |